. Author manuscript; available in PMC: 2024 Mar 1.

Published in final edited form as: Cancer Prev Res (Phila). 2023 Sep 1;16(9):523–530. doi: 10.1158/1940-6207.CAPR-23-0168

Table 5.

Hazard Ratios and P for Trend for Per Standard Deviation Increase in Liver Fibrosis Scores of Lethal and Fatal Prostate Cancer, Atherosclerosis Risk in Communities Study, 1990–1992

	Total^a		White		Black
	HR per SD increase in fibrosis score (95%CI)^c	P value for Trend^d	HR per SD increase in fibrosis score (95%CI)^c	P value for Trend^d	HR per SD increase in fibrosis score (95%CI)^c	P value for Trend^d
Lethal Prostate Cancer ^b
Events, No.	83		55		28
Person-years	92532		75263		17270
APR	1.02 (0.84,1.24)	0.80	0.91 (0.61,1.35)	0.09	1.08 (0.83,1.41)	0.13
FIB-4	1.03 (0.86,1.24)	0.67	1.00 (0.76,1.32)	0.77	1.06 (0.75,1.51)	0.84
NFS	1.04 (0.76,1.43)	0.61	1.22 (0.83,1.80)	0.44	0.74 (0.42,1.29)	0.79
Fatal Prostate Cancer
Events, No.	77		51		26
Person-years	105682		85453		20228
APR	0.89 (0.64,1.25)	0.79	0.83 (0.50,1.37)	0.17	0.89 (0.55,1.44)	0.36
FIB-4	0.95 (0.71,1.26)	0.70	0.98 (0.67,1.43)	0.62	0.90 (0.58,1.40)	0.95
NFS	1.06 (0.76,1.49)	0.50	1.31 (0.87,1.97)	0.24	0.71 (0.39,1.29)	0.64

All results were adjusted for the variables in model 3;

The associations for incidence among total, White, and Black are shown in Tables 2, 3, and 4, respectively;

The standard deviations (SD) for APRI, FIB-4, and NFS are 0.19, 0.68, and 1.41, respectively;

P value for trend was calculated by modeling the median of each quintile as a continuous term.