Table 1.
Baseline and Midlife (18-year follow up) characteristics of 695 women enrolled in longitudinal pregnancy cohort by lifetime history of infertilitya
| History of infertility N= 254 (36.6%) |
No infertility N=441 (63.4%) |
||||
|---|---|---|---|---|---|
| Baseline characteristics | mean | SD | mean | SD | b p value |
| Age at enrollment, years | 35.0 | 3.7 | 32.9 | 3.7 | <0.001 |
| Pre-pregnancy BMI, kg/m 2 | 24.8 | 5.3 | 24.4 | 5.0 | 0.30 |
| N | % | N | % | ||
| Race/ethnicity | 0.05 | ||||
| White | 196 | 77.2 | 311 | 70.8 | |
| Black | 20 | 7.9 | 62 | 14.1 | |
| Otherc | 38 | 15.0 | 66 | 15.0 | |
| College graduate | 216 | 85.0 | 335 | 76.3 | 0.01 |
| Married/cohabiting | 249 | 98.0 | 413 | 94.3 | 0.02 |
| Annual household income>$70,000 | 174 | 72.5 | 269 | 65.1 | 0.05 |
| History of depression | 43 | 19.3 | 44 | 11.1 | 0.01 |
| Ever smoker | 71 | 28.0 | 122 | 27.8 | 0.96 |
| Nulliparous d | 129 | 50.8 | 190 | 43.1 | 0.05 |
| Midlife characteristics | mean | SD | mean | SD | *p value |
| Age at midlife visit, years | 53.4 | 3.8 | 51.2 | 3.7 | <0.001 |
| BMI at midlife visit, kg/m2 | 28.2 | 6.5 | 27.7 | 6.6 | 0.30 |
| N | % | N | % | ||
| Lifetime number of pregnancies | 0.95 | ||||
| 1–3 | 162 | 63.8 | 281 | 64.0 | |
| ≥4 | 92 | 36.2 | 158 | 36.0 | |
| Cigarette use in past year | 6 | 2.5 | 12 | 2.8 | 0.79 |
| ≥12 months of amenorrhea | 155 | 61.8 | 174 | 39.9 | <0.001 |
a
The description was conducted in the non-multiple imputed dataset, N may not add up 695 due to missing values
b
P value: t-test for continuous ; chi-square test for categorical variables.
c
Other includes Asian or Pacific Islander (n= 41), Hispanic (n= 39), More than one race or ethnicity (n=23) and unclassified (n=1)
d
No pregnancy prior to index pregnancy