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. Author manuscript; available in PMC: 2024 Aug 1.
Published in final edited form as: Adv Drug Deliv Rev. 2023 Jun 28;199:114978. doi: 10.1016/j.addr.2023.114978

Figure 5.

Figure 5.

Super-resolution microscopy techniques for tracking absorption and transport of drug at the subcellular level. (A) SIM 3-color image of HeLa cells demonstrating NU-1000 (150 nm) uptake into cellular boundary. Nucleus colored in blue, early endosomes colored in magenta, NU-1000 colored in green. (B) SIM images of HeLa cells incubated with calcein-loaded temperature-treated NU-901 (cal@t.t.NU-901) at 30 min, 1 h, 2 h, 6 h, 8 h and 24 h. Lysosomes colored in magenta, cal@t.t.NU-901 colored in green. Fig. 5 reproduced from Ref [105].