Table 2.
Hypotheses
| Aim 1: Effectiveness | Prevalence of MDD in the 6 months after birth will be lower in ROSE than ECAU for: |
| 1a. people not at increased risk of PPD (defined using selective prevention) | |
| 1b. people at increased risk of PPD (defined using selective prevention) | |
| 1c. people not at increased risk of PPD (defined using indicated prevention) | |
| 1c. people not at increased risk of PPD (defined using indicated prevention) | |
| 1e. the sample as a whole (universal prevention) | |
| We will also explore whether ROSE prevents antenatal depression cases (universal) | |
| Aim 2: Cost-outcome comparison | Universal prevention will have lower net cost than selective or indicated prevention |
| 2a. From a societal perspective | |
| 2b. From a health system perspective | |
| Aim 5: Mechanisms | The effect of ROSE on PPD in the sample as a whole will be mediated by (a) instrumental support and (b) perceived stress. |