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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Contemp Clin Trials. 2023 Jul 18;132:107297. doi: 10.1016/j.cct.2023.107297

Table 6.

Dimensions of scalability of universal, selective, and integrated prevention to be assessed in qualitative interviews

ISAT domains • the problem (is it of sufficient concern to warrant scale-up to the proposed level?)
• the program/intervention (how well does it address needs of target group/problem?)
• strategic/political context (is problem consistent with policy/funding/strategic directions/priorities?)
• evidence of effectiveness (of ROSE as selective, indicated, or universal prevention)
• program/intervention costs (of ROSE as selective, indicated, or universal prevention)
• fidelity and adaptation (can program fidelity be monitored/maintained if implemented at scale?)
• reach and acceptability (of selective, indicated or universal prevention, esp to people from marginalized groups)
• delivery setting/workforce (feasibility/acceptability of selective, indicated, universal prevention in existing structures)
• are implementation infrastructure requirements of selective, indicated, universal prevention feasible for scale-up?
• sustainability (are integration, resourcing, workforce needed for selective, indicated, universal prevention sustainable at scale?)
IHI Model for going to Full Scale48,49 • support systems (learning systems, data systems, infrastructure, human capacity, capability for scale-up, sustainability)
• adoption mechanisms (leadership, communication, social networks, culture of urgency and persistence)
• content (develop and validate change package, replicate/adapt it across contexts)
Zamboni definition • the ability of a health intervention shown to be efficacious on a small scale or under controlled conditions to be expanded under real-world conditions to reach a greater proportion of the eligible population, while retaining effectiveness5052