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. 2023 Sep 21;12(18):2328. doi: 10.3390/cells12182328

Figure 6.

Figure 6

The cell survival rate in the Cep250 knockout mice at the age of 17 weeks. (A) Whole-mount immunostaining with phalloidin (green), anti-Cep250 antibody (red), and Dapi (blue) was performed through the whole cochlear turn. Tonotopic frequencies are noted. (B) The basal turn of the Cep250 knockout mouse showed a higher degeneration rate of the outer hair cell compared to that of WT mice. (C) Inner hair cell counts in apex, mid, and basal turns in CEP250 knockout mice. (D) Outer hair cell counts in apex, mid, and basal turns in Cep250 knockout mice. IHC, inner hair cells; OHC, outer hair cells; ns, not significant; ****, p < 0.001.