Table 2.
Separate multivariable logistic regression models for PADUA and RENAL predicting trifecta status (trifecta achieved vs. trifecta not achieved) in patients diagnosed with small renal masses between 2008 and 2021 and treated with ablation. Bootstrapped c-index represents the discrimination ability of the score generated by the models.
| PADUA Derived Score c-Index: 0.60 (0.53–0.67) |
RENAL Derived Score c-Index: 0.62 (0.55–0.69) |
||||||
|---|---|---|---|---|---|---|---|
| Model Items | Odds Ratio | 95% CI | p-Value | Model Items | Odds Ratio | 95% CI | p-Value |
| Polar location | Polar location | ||||||
| Upper/Lower | Ref | Entirely above or below the polar lines | Ref | ||||
| Crosses a polar line | 1.0 | (0.5–1.8) | 0.9 | ||||
| Middle | 0.8 | (0.5–1.4) | 0.5 | >50% crosses a polar line or crosses the axial renal midline or entirely between the polar lines | 0.6 | (0.3–1.4) | 0.3 |
| Exophytic rate | Exophytic rate | ||||||
| <50% | Ref | <50% | Ref | ||||
| ≥50% | 1.1 | (0.6–2.1) | 0.7 | ≥50% | 1.2 | (0.6–2.3) | 0.5 |
| Endophytic | 0.9 | (0.4–1.9) | 0.8 | Endophytic | 0.7 | (0.3–1.6) | 0.4 |
| Size (diameter) | Size (diameter) | ||||||
| ≤4 cm | Ref | ≤4 cm | Ref | ||||
| >4 cm | 3.4 | (1.7–6.8) | <0.001 | >4 cm | 3.7 | (1.8–7.5) | <0.001 |
| Renal sinus | Nearness to renal sinus or collecting system | ||||||
| Not involved | Ref | ≥7 mm | Ref | ||||
| 4–7 mm | 1.3 | (0.6–2.5) | 0.5 | ||||
| Involved | 1.0 | (0.5–2.1) | 0.9 | ≤4 mm | 6.1 | (3.0–12.5) | <0.001 |
| Urinary collecting system | |||||||
| Not involved | Ref | ||||||
| Dislocated/infiltrated | 2.3 | (1.2–4.5) | 0.01 | ||||
| Renal rim | |||||||
| Lateral | Ref | ||||||
| Medial | 1.3 | (0.8–2.2) | 0.3 | ||||
Bold values indicate statistical significance p < 0.05. CI: confidence interval.