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. 2023 Sep 15;13(18):2955. doi: 10.3390/diagnostics13182955

Table 2.

Separate multivariable logistic regression models for PADUA and RENAL predicting trifecta status (trifecta achieved vs. trifecta not achieved) in patients diagnosed with small renal masses between 2008 and 2021 and treated with ablation. Bootstrapped c-index represents the discrimination ability of the score generated by the models.

PADUA
Derived Score c-Index: 0.60 (0.53–0.67)
RENAL
Derived Score c-Index: 0.62 (0.55–0.69)
Model Items Odds Ratio 95% CI p-Value Model Items Odds Ratio 95% CI p-Value
Polar location Polar location
 Upper/Lower Ref  Entirely above or below the polar lines Ref
 Crosses a polar line 1.0 (0.5–1.8) 0.9
 Middle 0.8 (0.5–1.4) 0.5  >50% crosses a polar line or crosses the axial renal midline or entirely between the polar lines 0.6 (0.3–1.4) 0.3
Exophytic rate Exophytic rate
 <50% Ref  <50% Ref
 ≥50% 1.1 (0.6–2.1) 0.7  ≥50% 1.2 (0.6–2.3) 0.5
 Endophytic 0.9 (0.4–1.9) 0.8  Endophytic 0.7 (0.3–1.6) 0.4
Size (diameter) Size (diameter)
 ≤4 cm Ref  ≤4 cm Ref
 >4 cm 3.4 (1.7–6.8) <0.001  >4 cm 3.7 (1.8–7.5) <0.001
Renal sinus Nearness to renal sinus or collecting system
 Not involved Ref  ≥7 mm Ref
 4–7 mm 1.3 (0.6–2.5) 0.5
 Involved 1.0 (0.5–2.1) 0.9  ≤4 mm 6.1 (3.0–12.5) <0.001
Urinary collecting system
 Not involved Ref
 Dislocated/infiltrated 2.3 (1.2–4.5) 0.01
Renal rim
 Lateral Ref
 Medial 1.3 (0.8–2.2) 0.3

Bold values indicate statistical significance p < 0.05. CI: confidence interval.