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. Author manuscript; available in PMC: 2024 Sep 5.
Published in final edited form as: Cell Metab. 2023 Aug 16;35(9):1519–1529. doi: 10.1016/j.cmet.2023.07.010

Table 1 –

Ongoing clinical trials for multi-receptor agonists

Compound Stage Published Results
GLP1R/GCGR
LY3305677 Phase 1b 84
Cotadutide Phase 2b 83
BI-456906 Phase 1
Efinopegduite Phase 2 91
ATL-801 Phase 1
GLP1R/GIPR
Semaglutide + GIPR agonist Phase 1
GLP1R/GIPR/GCGR
SAR441255 Phase 1
LY3437943 Phase 2 92
HM15211 Phase 2
GLPIR/Amylin
Semaglutide + Cagrilintide Phase 1b 90