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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Biomaterials. 2023 Aug 11;301:122267. doi: 10.1016/j.biomaterials.2023.122267

Figure 7. Parallel analysis of photon and neutron sources of radiation for engineered cardiac (eCT) and bone marrow (eBM) tissues.

Figure 7.

(A) Top differentially expressed genes with highest absolute fold change in eCM tissues. (B) Selected key hypertrophy-related genes are increased in neutron-irradiated eCTs, normalized to GAPDH and photon controls. Data are shown as mean ± SD with unpaired t-tests with *p<0.05. (C) GO biological processes pathways enriched in differentially-expressed genes in eCT 4 Gy Photon versus 1 Gy Neutron comparative analysis. (D) Top differentially expressed genes with highest absolute fold change in eBM tissues. (E) Highest up- and down-regulated genes in CD14+ fraction of eBM-derived cells. (F) GO biological processes pathways enriched in differentially-expressed genes in eBM 4 Gy Photon versus 1 Gy Neutron comparative analysis.