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. Author manuscript; available in PMC: 2024 Aug 31.
Published in final edited form as: Vaccine. 2023 Aug 8;41(38):5494–5498. doi: 10.1016/j.vaccine.2023.07.067

Figure 2. Cellular response to vaccination as measured by PfCSP peptide IFNγ ELISPOT. Inset: Table of animal characteristics.

Figure 2.

A. Responses in liver lymphocytes obtained post-vaccination by surgery on day 56. B. Responses in liver lymphocytes from six days post-PfSPZ recall exposure at necropsy. C. Responses in PBMCs on days 0, 56, and 84. D. Responses in splenocytes from six days post-PfSPZ recall exposure at necropsy. Animal ID and vaccine treatment group given below x-axis. nSFU, normalized spot forming units. Animals were considered to have responded if nSFU per million cells was ≥10 fold greater than baseline for PBMCs or ≥10 fold greater than mock vaccinated controls for liver lymphocytes and splenocytes.