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. Author manuscript; available in PMC: 2023 Sep 27.
Published in final edited form as: Mucosal Immunol. 2023 Jun 7;16(4):551–562. doi: 10.1016/j.mucimm.2023.05.011

Fig. 6.

Fig. 6

IDO1-deficient Caco-2 cells have reduced HAstV1 infection and capsid spike protein binding. (A) Comparative infection of HAstV1 and Reovirus T1L infection with quantification at 1 dpi and (B) comparative binding of spike-GFP in WT and IDO1−/− cells. Comparisons between groups were assessed by an unpaired t-test with Welch’s correction and one-tailed p values indicated: ns, **** p < 0.0001. Data represent individual wells run in at least two independent experiments. dpi = days post infection; Ido1 = indoleamine 2,3-dioxygenase 1; GFP =; HAstV1 = human astrovirus-1; ns = non-significant; WT = wild-type.