Skip to main content
. Author manuscript; available in PMC: 2024 Aug 7.
Published in final edited form as: Curr Biol. 2023 Jun 26;33(15):3229–3237.e4. doi: 10.1016/j.cub.2023.06.012

Figure 4. Gadusol production has been lost in several species no longer exposed to UVR.

Figure 4

A, For each of 136 teleost species (full tree in Figure S4), we assessed various life history traits that identify habitats that may not require embryonic protection from UVR, including electroreception, live-bearing, cave dwelling, and deep-sea dwelling, indicated with colors in the legend to the left of the phylogeny. For each species, we identified the presence of intact open reading frames for eevs and/or MT-Ox. Species that have lost the genes required for gadusol production are indicated in red. We found 16 independent losses across this phylogeny. We found that fish with these traits are more likely than by chance to lose gadusol (p=0.012).

B, Examples of gadusol synthesis gene loss and pseudogenization in select species. Note Danio rerio has intact eevs and MT-Ox genes and is capable of gadusol production. See also Figures S1, S4 and Data S2).