Supplement 1. Correlation coefficients between Tanner staging and clinical or ultrasonographic variables in patients with cystic fibrosis.

Variable	N	R	P
Age	35	0.83	<0.01
Age at menarche	35	-0.78	<0.01
Uterine length	35	0.78	<0.01
Uterine transversal	35	0.72	<0.01
Uterine AP	35	0.71	<0.01
Uterine volume	35	0.75	<0.01
AP body-to-cervix ratio	35	0.64	<0.01
Longitudinal body-to-cervix ratio	35	0.62	<0.01
Endometrial thickness	25	0.46	0.02
Left ovary longitudinal size	34	0.72	<0.01
Transversal left ovary	34	0.82	<0.01
AP left ovary	34	0.59	<0.01
Left ovary volume	34	0.79	<0.01
Follicles number < 1 cm in left ovary	31	0.48	<0.01
Right ovary longitudinal size	34	0.56	<0.01
Transversal right ovary	34	0.59	<0.01
Right ovary AP	34	0.61	<0.01
Right ovary volume	34	0.62	<0.01
Follicles number < 1 cm right ovary	32	0.46	<0.01
Right uterine artery pulsatility index	29	-0.37	0.04
Left uterine artery pulsatility index	27	-0.54	<0.01
Mean uterine arteries pulsatility index	25	-0.56	<0.01
Bone age (years)	18	0.82	<0.01
Bone age (z-score)	35	0.40	0.01
Forced expiratory volume in 1 second (FEV1; z-score)	35	0.10	0.53
Forced vital capacity (FVC; z-score)	35	0.08	0.62
FEV1/FVC ratio	35	0.10	0.56
Shwachman-Kulczycki’s score	35	-0.08	0.61
Height	35	0.83	<0.01
Weight	35	0.90	<0.01
Body mass index (BMI)	35	0.75	<0.01
Height/age z-score	35	0.36	0.03

R: correlation coefficient; AP: anteroposterior; FEV1/FVC: Tiffeneau index.