Table 3. Clinical characteristics of 19 patients with X-linked hypophosphatemia (XLH) in the outpatient subcohort.
| Clinical characteristics | Values * | |
|---|---|---|
| Sex | ||
| Female | 13 (68.4%) | |
| Male | 6 (31.6%) | |
| Age | ||
| 0 to 3 years | 9 (47.4%) | |
| 4 to 10 years | 5 (26.3%) | |
| 11 to 20 years | 1 (5.3%) | |
| 21 to 30 years | 2 (10.5%) | |
| ≥ 31 years | 2 (10.5%) | |
| Age at diagnosis – mean (range) | 10.7 years (1.1 – 49.0 years) | |
| Follow-up duration – mean±SD | 126.5 ± 89.8 months | |
| Family history positive for XLH | 9 (47.4%) | |
| Lumbar spine deformity | 7 (36.8%) | |
| Cranial deformity | 3 (15.8%) | |
| Epiphyseal enlargement | 10 (52.6%) | |
| Bone pain | 15 (78.9%) | |
| Teeth abnormalities (except for cavities) | 5 (26.3%) | |
| Lower limb deformity | 17 (89.5%) | |
| Fragility fractures | 9 (47.4%) | |
| Femoral | 5 | |
| Others | 4 | |
| Orthopedic surgery (osteotomy) | 9 (47.4%) | |
| Renal complications | 4 (33.3%) | |
| Nephrolithiasis | 1 | |
| Nephrocalcinosis | 1 | |
| Hydronephrosis | 1 | |
| Membranous nephropathy | 1 | |
*
Number of patients (range or percentage in relation to the entire cohort).