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. 2020 Jun 19;64(6):687–694. doi: 10.20945/2359-3997000000271

Table 3. Biochemical profile.

Case Diagnosis Cortisol 8 am Cortisol LLDST ug/dL Cortisol HDDST ug/dL UFC ug/24 h! ACTH pg/mL Lowest potassium mEq/lt
1 Occult 68 NR NR 3350 265 1.8
2 Metastatic medullary thyroid carcinoma 27.4 24 NR 2600 NR 2.6
3 Well-differentiated pancreatic neuroendocrine tumor 21.7 7.7 7.2* NA 31.8 3
4 Lung carcinoid 21 24.5† 22.2 4.5† 18.42 - NR - NR 401.4† NA
5 Small-cell lung carcinoma 33.66 22.6 30.61 NR 32.5 1.3
6 Lung carcinoid with liver and bone metastases. NR 28.8 NR 3994 93.7 2.2
7 Probable small-cell lung carcinoma NR 44.6 > 120 6963 115.9 1.7
8 Grade 3 pancreatic neuroendocrine carcinoma with liver metastasis NR 45.9 48.5 6487 10.2 2.1
9 Lung carcinoid 34.2 32.5 28.9 283 88.3 2.8
10 Pheochromocytoma 19.4 23.8 2.1* 98 25.8 4.03
11 Poorly-differentiated lung neuroendocrine carcinoma with liver metastasis - 58.9 - 7530 79.9 1.8
12 Grade 2 pancreatic neuroendocrine carcinoma with liver metastasis 58.7 NR 63.7 196.3 135.6 1.9
13 Metastatic thymoma 21 49 29 1478 144 2.7
14 Small-cell lung carcinoma 60 60 - 253 765 2.1

ACTH: Adrenocorticotropic hormone; UFC: 24-hour urinary free cortisol; NA: not available; NR: not realized; LLDST: low-dose dexamethasone suppression test (LDDST); HDDST: high-dose dexamethasone suppression test.

! Reference levels differ according to laboratory (HSVF 58-243 ug/24 h, HPTU 50-190 ug/24 h)

† At the time of recurrence.

* Suppression of plasma cortisol after HDDST by 50 percent of basal value.