Table 3. Biochemical profile.
| Case | Diagnosis | Cortisol 8 am | Cortisol LLDST ug/dL | Cortisol HDDST ug/dL | UFC ug/24 h! | ACTH pg/mL | Lowest potassium mEq/lt |
|---|---|---|---|---|---|---|---|
| 1 | Occult | 68 | NR | NR | 3350 | 265 | 1.8 |
| 2 | Metastatic medullary thyroid carcinoma | 27.4 | 24 | NR | 2600 | NR | 2.6 |
| 3 | Well-differentiated pancreatic neuroendocrine tumor | 21.7 | 7.7 | 7.2* | NA | 31.8 | 3 |
| 4 | Lung carcinoid | 21 24.5† | 22.2 4.5† | 18.42 - | NR - | NR 401.4† | NA |
| 5 | Small-cell lung carcinoma | 33.66 | 22.6 | 30.61 | NR | 32.5 | 1.3 |
| 6 | Lung carcinoid with liver and bone metastases. | NR | 28.8 | NR | 3994 | 93.7 | 2.2 |
| 7 | Probable small-cell lung carcinoma | NR | 44.6 | > 120 | 6963 | 115.9 | 1.7 |
| 8 | Grade 3 pancreatic neuroendocrine carcinoma with liver metastasis | NR | 45.9 | 48.5 | 6487 | 10.2 | 2.1 |
| 9 | Lung carcinoid | 34.2 | 32.5 | 28.9 | 283 | 88.3 | 2.8 |
| 10 | Pheochromocytoma | 19.4 | 23.8 | 2.1* | 98 | 25.8 | 4.03 |
| 11 | Poorly-differentiated lung neuroendocrine carcinoma with liver metastasis | - | 58.9 | - | 7530 | 79.9 | 1.8 |
| 12 | Grade 2 pancreatic neuroendocrine carcinoma with liver metastasis | 58.7 | NR | 63.7 | 196.3 | 135.6 | 1.9 |
| 13 | Metastatic thymoma | 21 | 49 | 29 | 1478 | 144 | 2.7 |
| 14 | Small-cell lung carcinoma | 60 | 60 | - | 253 | 765 | 2.1 |
ACTH: Adrenocorticotropic hormone; UFC: 24-hour urinary free cortisol; NA: not available; NR: not realized; LLDST: low-dose dexamethasone suppression test (LDDST); HDDST: high-dose dexamethasone suppression test.
! Reference levels differ according to laboratory (HSVF 58-243 ug/24 h, HPTU 50-190 ug/24 h)
† At the time of recurrence.
* Suppression of plasma cortisol after HDDST by 50 percent of basal value.