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(A) Patients with IQSEC2 null variants present more severe behavioral features (B) Disorders in initiating and maintaining sleep (SDSC DIMS) and altered perception of health wellbeing (QI-Dis Health wellbeing) in IQSEC2-patients with null variants. Legend: RSBQ NonCat = RSBQ items not categorized; SDSC DIMS = disorders in initiating and maintaining sleep; and QI-Dis Health wellbeing = Quality of Life Inventory-Disability health wellbeing.
