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. Author manuscript; available in PMC: 2023 Sep 27.
Published in final edited form as: Cell Rep. 2023 Jul 31;42(8):112889. doi: 10.1016/j.celrep.2023.112889

Figure 7. Microglial-specific deletion of Igf1r abolishes the neuroprotective effect of IGFBPL1 in glaucomatous mice.

Figure 7.

(A) IOP profiles of tamoxifen-treated fl/fl and IrKO mice that received PBS or IGFBPL1 treatments.

(B–E) pSTR amplitudes (B), CS (C), VA (E), and RGC counts in retinal flat mounts of sham- or MB-injected fl/fl and IrKO mice that received PBS or IGFBPL1 treatments. *p < 0.05, **p < 0.01, ***p < 0.001; one-way ANOVA with Tukey’s multiple comparisons test (n > 5 mice/group).

Data are mean ± SEM.

See also Figure S7.