Table 5.
t-ratio, p value 95% CI | ||||
---|---|---|---|---|
Variables | ANOVA Model, p value | CN-Dementia | CN-MCI | MCI-Dementia |
CSF Aβ 1–42 | F(2,45) = 3.28, p = 0.047 | −2.50, 0.04 [−1460.52 – 23.12] | - | - |
CSF t-tau | F(2,45) = 7.25, p = 0.002 | 3.81, 0.001 [77.87–350.55] | - | 2.97, 0.01 [32.16 – 316.99] |
CSF p-tau | F(2,45) = 7.44, p = 0.002 | 3.86, 0.001 [8.41 – 36.86] | - | 2.96, 0.01 [3.31 – 33.03] |
Only measures with significant clinical group differences (p < 0.05) following post hoc Tukey’s HSD test shown. No additional covariates added to models.
Abbreviations: Aβ1–42 = amyloid beta 1–42 peptide; ANOVA = analysis of variance; CN = cognitively normal; CSF = cerebrospinal fluid; HSD = honestly significant difference; MCI = mild cognitive impairment; p-tau = phosphorylated tau; t-tau = total tau