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. Author manuscript; available in PMC: 2024 Aug 21.
Published in final edited form as: Angew Chem Int Ed Engl. 2023 Jul 13;62(34):e202303415. doi: 10.1002/anie.202303415

Figure 5.

Figure 5.

Depth of coverage in WWA compared to a traditional LFQ single-cell dataset. (A) The number of proteins detected based on the copy number for three datasets: a bulk proteome study,[14] the new WWA data (present study, blue), and data from our previous LFQ single-cell study (2021 study, orange).[5c] (B and C) A Gene Ontology analysis shows that the wide-window acquisition is able to achieve greater depth for proteins whose processes (B) and functions (C) are important to cancer development and cellular physiology. The scale in (B) and (C) are the portion of detected proteins relative to the bulk study.[14]