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. Author manuscript; available in PMC: 2024 Jul 19.
Published in final edited form as: Nucl Med Biol. 2023 Jul 19;122-123:108368. doi: 10.1016/j.nucmedbio.2023.108368

Table 1:

The [77Br]RD1 pharmacological parameters calculated from total and nonspecific binding studies in the various ovarian cancer cell lines and their corresponding 95% CI.

Ovarian
Cancer Cell Line
Bmax (95% CI)
(attomol/cell)
Kd(95% CI)
(nM)
NS (95% CI)
(attomol/cell/nM)
ID8 3.0 (2.4–3.9) 31 (20–49) 0.049 (0.047–0.052)
OVCAR8 1.6 (1.4–1.8) 6.0 (4.2–8.2) 0.050 (0.048–0.052)
OVCAR8 PARP1-KO 0.83 (0.50–1.5) 7.5 (2.7–20) 0.039 (0.033–0.046)
UWB1.289 11 (7.9–16) 24 (10–57) 0.20 (0.19–0.21)
UWB1.289+BRCA1 8.6 (6.6–11) 25 (13–48) 0.26 (0.25–0.26)