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Rats experiencing eFSE at developmental critical periods of entorhinal-hippocampal development exhibit spatial cognitive deficits as adults. (a) Dwell-time (left), path (middle), and circular statistics (right) relative to shock zone (red triangle) for a representative normothermic CTL (top) and eFSE animal (bottom). During 16 training sessions distributed over 2 days, rats with eFSE receive more shocks (b) and make more shock zone entrances (c) than normothermic CTL animals.
