Table 2.

Top 20 differentially methylated CpGs between SLE cases and controls

CpG	Gene	Chr	Position	CpG Position in Gene	AA Control β	AA LN− β	AA LN+ β	EA Control β	EA LN− β	EA LN+ β	p-value	FDR-adjusted p-value
cg13452062	IFI44L	1	79088559	5’UTR	0.703	0.177	0.134	0.798	0.843	0.08	1.439E-09	0.001
cg10549986	RSAD2	2	7018153	1stExon	0.443	0.132	0.153	0.418	0.333	0.099	4.194E-09	0.001
cg21549285	MX1	21	42799141	5’UTR	0.714	0.232	0.195	0.744	0.788	0.156	7.607E-09	0.002
cg00959259	PARP9	3	122281975	5’UTR	0.501	0.198	0.226	0.537	0.523	0.161	1.714E-08	0.003
cg16400320	NA	8	144105210	NA	0.919	0.807	0.808	0.907	0.887	0.781	3.876E-08	0.005
cg18693345	C5orf38	5	2754148	Body	0.149	0.184	0.172	0.136	0.269	0.238	4.986E-08	0.006
cg11702942	LY6E	8	144102584	Body	0.799	0.636	0.633	0.778	0.757	0.628	7.439E-08	0.007
cg07815522	PARP9	3	122282157	5’UTR	0.623	0.277	0.284	0.649	0.704	0.234	9.795E-08	0.009
cg22862003	MX1	21	42797588	TSS1500	0.535	0.265	0.281	0.581	0.635	0.242	1.351E-07	0.011
cg24678928	DDX60	4	169240829	TSS1500	0.787	0.478	0.461	0.83	0.808	0.371	1.708E-07	0.012
cg10959651	RSAD2	2	7018020	1stExon	0.424	0.099	0.113	0.341	0.26	0.058	1.843E-07	0.012
cg08924203	MX1	21	42798747	5’UTR	0.148	0.073	0.061	0.125	0.123	0.051	2.461E-07	0.014
cg22016995	IRF7	11	614787	Body	0.969	0.912	0.877	0.973	0.971	0.893	3.064E-07	0.014
cg01079652	IFI44	1	79118191	Body	0.915	0.577	0.507	0.91	0.889	0.47	3.213E-07	0.014
cg14943355	PARP11	12	3980704	5’UTR	0.484	0.235	0.235	0.532	0.568	0.209	3.254E-07	0.014
cg17593958	PRIC285	20	62199034	5’UTR	0.127	0.215	0.244	0.086	0.093	0.192	3.363E-07	0.014
cg20791089	FBRS	16	30669590	TSS1500	0.084	0.112	0.102	0.079	0.14	0.118	3.377E-07	0.014
cg25998594	IRF9	14	24632095	Body	0.862	0.716	0.730	0.852	0.861	0.689	3.967E-07	0.016
cg06899530	ILDR2	1	166916866	Body	0.068	0.047	0.051	0.062	0.047	0.048	4.726E-07	0.018
cg06561932	LOC389641	8	23081981	TSS1500	0.049	0.041	0.039	0.059	0.047	0.041	5.145E-07	0.018