Table 4.
Significantly changing prohormone-derived hypothalamus peptides identified from the Dec.-Jan. (IBA) vs. Dec.-Feb. (Torpor) comparison.
| Peptide Sequencea | Peptide Nameb | Gene | FC(log2)c |
|---|---|---|---|
| Q(−17.03)EDAELQPR | CARTPT | 1.57 | |
| FLGEAYHHVPESQRD | CHGB | 1.25 | |
| LGVLFNPYYDPLQWKSSRFE | CHGB | 0.94 | |
| Q(−17.03)YDRVAELDQLLHY | BAM-1745 | CHGB | 1.03 |
| YGGFLRKYP | β-neoendorphin | PDYN | 1.24 |
| MDELYPVEPEEEANGGEVL | PENK | 1.72 | |
| MDELYPVEPEEEANGGEVLA | PENK | 2.19 | |
| SPQLEDEAKEL | PENK | 1.34 | |
| VGRPEWWMDYQ | PENK | 1.60 | |
| YGGFMRF | Met-enkephalin-Arg-Phe | PENK | 1.23 |
| YGGFMRGL | Met-enkephalin-Arg-Gly-Leu | PENK | 1.05 |
| ALNSVAYERNAMQNY | C-terminal flanking peptide(1-15) | TAC1 | 1.21 |
| ALNSVAYERNAMQNYE | C-terminal flanking peptide | TAC1 | 1.53 |
| ASWTREPLE | TRH | 1.18 |
a
Post-translational modifications are indicated by mass change observed by mass spectrometry. Pyroglutamylation = (−17.03).
b
Peptide common names inferred from analogy to well-annotated rat sequence.
c
Fold-change values are given for IBA/Torpor comparison. A positive value indicates the peptide is higher abundance in IBA.