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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2023 Aug 20;476:116659. doi: 10.1016/j.taap.2023.116659

Figure 2. Concordance between the SYSTEMETRIC® Cell Health Screen and ZBEscreen™.

Figure 2.

A) Venn diagram showing the number of bioactive chemicals between the ZBEscreen™ and SYSTEMETRIC® CHS B) Distribution of CHI™ bioactives and ZBEscreen™ endpoints across the 87 DNT chemical library where the zebrafish endpoints were separated by mortality, morphology, and the behavioral assessments EPR and LPR (green indicates bioactivity identified by CHI, blue indicates bioactivity identified by any of the 4 zebrafish readouts). Likewise, DNT chemicals not identified through the CHI™ classification were detected by the ZBEscreen™, demonstrating the complementarity between the systems used in tandem.