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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2023 Aug 20;476:116659. doi: 10.1016/j.taap.2023.116659

Figure 5. Links between the distinct physiological subsystems tested.

Figure 5.

The graphical network model shows each assay readout as a node in a graph, and edges between nodes represent conditional dependencies between assays’ endpoints. The presence and line thickness show the strength of these dependencies (a thicker line indicates stronger association). For the sake of clarity, readouts without corresponding edges are omitted from the network. The blue points indicate CompTOX-curated assay endpoints, whereas the red and green points represent ZBEscreen™ and CHS endpoint readouts, respectively.