Table 1. Surveillance case definitions of human NiV infection.
Case definition | Criteria |
---|---|
Nipah like illness (Screening case definition) | Fever (axillary temperature >38.5°C) or history of raised temperature prior to hospitalization AND any sign/symptom of brain pathology OR Fever (axillary temperature >38.5°C) or history of raised temperature prior to hospitalization AND any sign/symptom of lung pathology |
Suspected Nipah encephalitis | Fever or history of fever (axillary temperature >38.5°C) AND evidence of acute brain pathology (e.g., altered mental status, new-onset seizures, or new neurological deficit either diffuse or localized to the brain) |
Suspected Nipah pneumonitis | Onset of illness within the last seven days AND fever or history of fever (axillary temperature >38.5°C) AND severe shortness of breath (i.e., dyspnea that prevents the patient from walking unassisted for not more than ten steps) AND chest radiograph consistent with diffuse acute respiratory distress syndrome |
Probable Nipah infection | History of Nipah encephalitis or pneumonitis AND established epidemiological link with at least one confirmed Nipah case but the absence of laboratory confirmation due to the patient’s death |
Confirmed Nipah infection | Laboratory confirmation of the infection; either by identification of anti-Nipah IgM via ELISA (Enzyme-linked immunosorbent assay) OR through identification of viral particles by qRT-PCR (quantitative reverse transcription polymerase chain reaction) with or without a history of Nipah encephalitis/pneumonitis |