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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: J Subst Use Addict Treat. 2023 May 23;153:209081. doi: 10.1016/j.josat.2023.209081

Table 2.

Key observations for AI/AN participants in each conceptual contribution

Author(s) and date CTN Protocol # Type of source Key contributions for AI/AN peoples
1. Burlew et al., 2020 0018; 0019; 0021; 0033 Perspective, opinion, or commentary Limited information is available for community engaged, collaborative, cultural adaptation of effective interventions. A study of substance use among AI/AN communities was one of the earliest efforts within the CTN to consider the role of culture in treatment and the need for community participation.
2. Burlew et al., 2011a NR Perspective, opinion, or commentary A CTN partnership with the Na’nizhoozhi Center, an AI/AN substance use treatment program, exemplified how cultural adaptations and community based participatory research strategies increase efficacy, acceptability, and inclusion of substance use treatment for underrepresented ethnoracial groups within the CTN.
3. Burlew et al., 2011b 0004; 0006; 0007; 0013; 0014; 0015; 0018; 0020; 0020-A-1; 0029; 0042-S Perspective, opinion, or commentary AI/AN studies are used to demonstrate community based participatory research strategies for recruitment, treatment access, retention, measurement, and appropriate analyses related to CTN research among underrepresented ethnoracial groups.
4. Carroll et al., 2007 NR Conference proceedings The CTN is an ideal avenue for research addressing unmet substance use needs among underrepresented ethnoracial groups. For AI/AN groups, this is supported by the Native American Workgroup who advocates for more Indigenous inclusion at all levels; by challenging stigma and addressing historical trauma; and by the CTN partnering with AI/AN Tribes.
5. Perl, 2011 0033 Perspective, opinion, or commentary To support more resources for implementation science for addiction treatment, three strategies are identified: (1) developing scientific tools to better understand implementation; (2) building an implementation workforce; and (3) including clinicians at the start to have more relevant research. Successful examples include three collaborations between academic partners and AI/AN Tribal entities.
6. Thomas et al., 2011 0033 Perspective, opinion, or commentary Five partnerships between academic institutions and AI/AN Tribes/organizations that represented community based participatory research observed common themes for addressing barriers and establishing successful partnerships included community driven research; contextualized community knowledge and protocols; destigmatizing and trust building methods; researcher personal responsibility; proper use of Institutional Review Boards; and inclusion of Indigenous researchers and cultural values

Note. AI/AN = Alaska Native/American Indian; CTN = Clinical Trials Network; NR = Not Reported.