Figure 1.
Endothelial Glycocalyx in Aging and Age-related Diseases. GPs, glycoproteins; HS, heparan sulfate; CS, chondroitin sulfate; KS, keratan sulfate; HA, hyaluronic acid; SA, sialic acid; HPSE, heparinase; HAase, hyaluronidase; EG, endothelial glycocalyx; MMPs, matrix metalloproteinases; ADAM, A disintegrin and metalloproteinase; HDAC, histone deacetylase; TIMPs, tissue inhibitor of matrix metalloproteinases; NO, nitric oxide; Nrf2, nuclear factor erythroid 2-related factor 2; Aβ, amyloid-beta. Created with BioRender.com.