Table 3.
Hazards ratio (95% confidence interval) for new thrombosis in patients with Chuvash erythrocytosis.
Baseline values | Hazards ratio (univariate) | P | Hazards ratio (multivariate*) | P | Hazards ratio (multivariate)** | P |
---|---|---|---|---|---|---|
Erythropoietin (IU/L; natural log) | 1.69 (1.23-2.33) | 0.001 | 1.71 (1.25-2.34) | 0.0008 | 1.59 (1.11-2.28) | 0.011 |
Hematocrit (%) | 0.97 (0.94-1.01) | 0.21 | 0.99 (0.94-1.03) | 0.51 | 0.98 (0.94-1.02) | 0.41 |
Ferritin (μg/L; natural log) | 1.37 (.925-2.03) | 0.12 | 1.08 (0.73—1.61) | 0.70 | 1.25 (0.83—1.88) | 0.29 |
Transferrin (mg/ml) | 0.28 (0.15-0.53) | 0.0009 | 0.28 (0.12- 0.63) | 0.002 | 0.29 (0.19- 0.71) | 0.007 |
Erythropoietin, hematocrit, ferritin, and transferrin are all included in the model.
Additionally adjusted for age at baseline, past history of phlebotomy, and past history of thrombosis.