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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Alzheimers Dement. 2023 Apr 10;19(9):3902–3915. doi: 10.1002/alz.13075

Figure 2. Differential chromatin accessibility and expression of APOE in Astrocyte cluster 1.

Figure 2.

A) APOE expression represented in clusters generated by the integrated snATAC-seq and snRNA-seq data; B) Visualization of chromatin differential accessible peaks in the APOE locus between ancestries from Astrocyte cluster 1. *Represents significantly differentially accessible peaks between ancestries (*FDR=0.02; ***FDR=0.001). C) Venn diagram showing transcription factors biding to APOE that are differentially expressed (DEG) and differentially accessible (DAG).