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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Alzheimers Dement. 2023 Apr 10;19(9):3902–3915. doi: 10.1002/alz.13075

Table 2.

Differentially accessible peaks in promoter regions of Local Ancestry genes in Astrocyte cluster 1.

Gene Chromosome Peak location Distance to TSS FC FDR Region
CTB-171A8.1 chr19 44718456 −21 3.66 0.003 promoter-TSS
BCL3 chr19 44748309 12 2.77 0.007 promoter-TSS
BCAM chr19 44808802 −7 5.11 0.043 promoter-TSS
BCAM chr19 44808802 −51 5.11 0.043 promoter-TSS
CTB-129P6.4 chr19 44890205 421 2.70 0.002 promoter-TSS
TOMM40 chr19 44890205 −781 2.70 0.002 promoter-TSS
APOE* chr19 44903514 −1990 4.52 0.022 promoter-TSS
APOE* chr19 44905485 −19 2.57 0.001 promoter-TSS
APOC1 chr19 44914897 278 2.05 0.000 promoter-TSS
APOC1 chr19 44914897 900 2.05 0.000 promoter-TSS
APOC1P1 chr19 44926992 266 2.23 0.025 promoter-TSS
CLPTM1 chr19 44955080 84 3.61 0.007 promoter-TSS
CLPTM1 chr19 44955080 84 3.61 0.007 promoter-TSS
CTB-179K24.3 chr19 45091377 −1236 2.19 0.027 promoter-TSS
PPP1R37 chr19 45091377 −1335 2.19 0.027 promoter-TSS
MARK4* chr19 45294609 504 3.65 0.011 promoter-TSS
ERCC2 chr19 45370425 −88 2.40 0.002 promoter-TSS
ERCC2 chr19 45370425 −57 2.40 0.002 promoter-TSS
PPP1R13L chr19 45405279 −491 3.68 0.004 promoter-TSS
CD3EAP chr19 45405279 −1162 3.68 0.004 promoter-TSS
PPP1R13L chr19 45405279 820 3.68 0.004 promoter-TSS
FOSB chr19 45467194 −551 2.61 0.024 promoter-TSS
VASP chr19 45506348 −818 3.58 0.020 promoter-TSS
OPA3 chr19 45584758 −166 2.16 0.000 promoter-TSS
EML2* chr19 45644874 505 7.63 0.032 promoter-TSS
EML2* chr19 45645399 −20 3.28 0.002 promoter-TSS
FBXO46 chr19 45730087 567 4.28 0.025 promoter-TSS
FBXO46 chr19 45730692 −38 2.01 0.028 promoter-TSS
FBXO46 chr19 45730692 −38 2.01 0.028 promoter-TSS
RSPH6A chr19 45815742 −673 3.10 0.033 promoter-TSS
IRF2BP1 chr19 45885449 471 4.72 0.025 promoter-TSS
NOVA2 chr19 45973825 −529 5.11 0.004 promoter-TSS
CCDC61 chr19 45995053 −158 2.38 0.000 promoter-TSS
CCDC61 chr19 45995053 −164 2.38 0.000 promoter-TSS

FC: Fold change; TSS: Transcription Starting Site; Negative value in Distance to TSS reflects peaks falling upstream of TSS