Table 2.
Project | Disease/ phenotype |
Data type | Populationsa | Reference(s) | URL |
---|---|---|---|---|---|
All of Us | Various | Genome sequence, omics data, and EHR | Black, African American or African; Asian; Hispanic Latino or Spanish; and White | 2, 129 | https://allofus.nih.gov/ |
Ancestry Networks for the Human Cell Atlas | Healthy human cell | Single-cell multiomics | African, African American, Afro-Caribbean, Asian, Latinx, and Middle Eastern populations | 130 | https://chanzuckerberg.com/rfa/ancestry-networks-human-cell-atlas/ |
Global Biobank Meta-Analysis Initiative | Various | Genotype and EHR | Global populations | 131 | https://www.globalbiobankmeta.org/ |
H3 Africa | Various | Genotype and EHR | African | 132 | https://h3africa.org/ |
The PAGE Study | Various | Genotype and phenotype | African American, Asian, Hispanic/Latino, Native American, Native Hawaiian | 133 | https://www.pagestudy.org/ |
TOPMed | Heart, lung, blood, and sleep disorders | Multiomics | African, Asian, European, and Hispanic/Latino ancestry populations | 134 | https://topmed.nhlbi.nih.gov/ |
WW-ADNI | Alzheimer’s disease | Genotype and image | Argentina, Australia, Canada, China, Japan, Korea, Mexico, North America, and Taiwan | 118 | https://www.alz.org/research/for_researchers/partnerships/wwadni |
The original terms from the information sources are used.
The Global Biobank Meta-Analysis Initiative includes 24 biobanks with more than 2.2 million genotyped samples (as of January 2023) from different origins and ancestries (https://www.globalbiobankmeta.org/). Of the 24 biobanks, 9 are in North America, 8 are in Europe, 5 are in Asia, 1 is in Africa, and 1 is in Australia.
Abbreviations: EHR, electronic health record; H3 Africa, Human Heredity and Health in Africa; PAGE, Population Architecture using Genomics and Epidemiology; TOPMed, Trans-Omics for Precision Medicine; WW-ADNI, Worldwide Alzheimer’s Disease Neuroimaging Initiative.