Plasma neurofilament light chain (NFL) concentration values in the TODAY cohort and external control cohort without diabetes.
Panel A--Boxplots of LN[NFL] (pg/mL) values at Assessment 4 in the TODAY/TODAY2 participants with and without DN. Panel B – Bar graph of NFL concentrations (pg/ml) in TODAY/TODAY2 participants compared to external controls without diabetes at Assessment 4. Statistically significant (p value: *p < 0.05, **p < 0.01, ***p <0.001).