Table 3.

GLM analyses of prospective preoperative predictors of days per week of opioid use at post-TKA follow-up.

	6-Week Follow-Up					6-Month Follow-Up
Preoperative Predictor	Beta	SE	P value	Adj OR	95% CI	Beta	SE	P value	Adj OR	95% CI
Preoperative Opioid Use	1.344	0.452	.003	3.83	1.58, 9.31	5.727	1.283	<.001	307.19	24.86, 3796.07
HOME-Euphoric Response	−0.020	0.163	.902	0.98	0.71, 1.35	0.615	0.276	.026	1.85	1.08, 3.18
HOME-Opioid Exposure	0.417	0.113	<.001	1.52	1.22, 1.89	2.958	0.892	<.001	19.26	3.36, 110.54
CES-D	0.101	0.022	<.001	1.11	1.06, 1.15	0.130	0.035	<.001	1.14	1.06, 1.22
CATS	0.053	0.013	<.001	1.05	1.03, 1.08	0.091	0.024	<.001	1.10	1.05, 1.15
STAI	0.031	0.015	.035	1.03	1.01, 1.06	0.060	0.023	.009	1.06	1.02, 1.11
MBM	−0.030	0.047	.520	0.97	0.89, 1.06	0.095	0.071	.183	1.10	0.96, 1.26
PROMIS Pain Interference	0.065	0.023	.005	1.07	1.02, 1.12	0.108	0.040	.007	1.11	1.03, 1.21
PROMIS Sleep Disturbance	0.063	0.020	.001	1.07	1.03, 1.11	0.163	0.039	<.001	1.18	1.09, 1.27
Temporal Summation of Pain	0.360	0.105	<.001	1.43	1.17, 1.76	0.786	0.204	<.001	2.20	1.47, 3.28

Note: Analyses of the continuous days per week of opioid use outcome specified a negative binomial distribution.

Significant results are highlighted in bold text. TKA = Total Knee Arthroplasty, HOME = History of Opioid

Medical Exposure, CES-D = Center for Epidemiological Studies Depression Scale, CATS = Catastrophizing

Scale, STAI = State Trait Anxiety Inventory, MBM = Michigan Body Map