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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Brain Behav Immun. 2023 Jul 10;113:248–258. doi: 10.1016/j.bbi.2023.07.003

Figure 6: Morris water maze performance 3 months after treatment cessation.

Figure 6:

There was no effect of treatment history on acquisition across 4 training days at the delayed timepoint (Panel A). There is no effect of PB or RRS history on the time spent swimming in the target quadrant (Panel B) or swimming velocity (Panel C) during the 1-hour probe trial. Rats with a history of PB treatment spent significantly less time in the target quadrant during the 24-hour probe trial (Panel D) but swim speed was not different between groups (Panel E). When the platform was visible, there was no effect of treatment history on escape latency (Panel F) or path length (Panel G). All data are expressed as mean + SEM, n = 13–15/group. [*: Significant effect of PB, p < 0.05].