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. Author manuscript; available in PMC: 2024 Aug 4.
Published in final edited form as: J Org Chem. 2023 Jul 13;88(15):10881–10904. doi: 10.1021/acs.joc.3c00917

Table 8.

Silver catalyzed decarboxylation of α-fluoroacrylic acids to disubstituted vinyl fluorides.a

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a

Assay yields from 19F NMR versus PhCF3 are given in brackets, isolated yields are given with no brackets. E/Z isomeric purity of isolated product is given under yields. Isomeric purity determined by 19F NMR. For detailed reaction conditions, see the Experimental Section.

b

AgOAc loading of 50 mol %.