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. Author manuscript; available in PMC: 2024 Sep 20.
Published in final edited form as: Cell Syst. 2023 Aug 23;14(9):777–787.e5. doi: 10.1016/j.cels.2023.07.007

KEY RESOURCES TABLE

REAGENT or RESOURCE SOURCE IDENTIFIER
Deposited data
CPTAC Pan-Cancer Data used in this study Li et al, accepted, Cancer Cell, CANCER-CELL-D-22–00603 https://kb.linkedomics.org/download
GENCODE V34 basic (CHR) 32 https://www.gencodegenes.org/human/release_34.html
DrugBank version 5.1.9 33 https://go.drugbank.com
Guide to Pharmacology version 2022.2 34 https://www.guidetopharmacology.org
Cell Surface Protein Atlas 35 https://wlab.ethz.ch/cspa/
PhosphoSitePlus 31 https://phosphosite.org
Drug Gene Interaction Database version 2022-Feb 36 https://www.dgidb.org
Cancer Gene Census 37 https://cancer.sanger.ac.uk/cosmic/download
Tumor suppressor genes from Bailey et al 38 Table S1
Tumor suppressor genes from Tokheim et al 39 Table S1
PTMsigDB v1.9 40 https://github.com/broadinstitute/ssGSEA2.0/tree/master/db/ptmsigdb
KinBase 41 http://kinase.com/web/current/
DEPOD 42 http://www.depod.bioss.uni-freiburg.de/download.php
CellTalkDB v1.0 43 https://github.com/ZJUFanLab/CellTalkDB
Transcription factor database 44 http://humantfs.ccbr.utoronto.ca
DepMap: Pan-cancer essential genes 45 https://depmap.org/portal/download/
Software and algorithms
Metap v1.4 46 https://cran.r-project.org/web/packages/metap/index.html
WebGestalt 19 https://www.webgestalt.org
GISTIC2.0 47 ftp://ftp.broadinstitute.org/pub/GISTIC2.0/GISTIC_2_0_23.tar.gz
ssGSEA 2.0 40 https://github.com/broadinstitute/ssGSEA2.0
Strelka v2 48 https://github.com/Illumina/strelka
MUTECT v1.7 49 https://software.broadinstitute.org/cancer/cga/mutect_download
VarScan v2.3.8 50 http://dkoboldt.github.io/varscan/
Pindel v0.2.5 51 https://github.com/genome/pindel
CrossMap v0.5.3 52 https://crossmap.sourceforge.net/
MutSigCV v1.41 53 https://software.broadinstitute.org/cancer/cga/mutsig
ANNOVAR v04.16.2018 54 https://annovar.openbioinformatics.org/en/latest/
CopywriteR v2.0.6 55 https://www.bioconductor.org/packages/release/bioc/html/CopywriteR.html
CIRI v2.0.6 56 https://sourceforge.net/projects/ciri/
BWA v0.7.17-r1188 57 https://bio-bwa.sourceforge.net/
RSEM v1.3.1 58 http://deweylab.github.io/RSEM/
Bowtie2 v2.3.3 59 https://bowtie-bio.sourceforge.net/bowtie2/index.shtml
MSFragger v3.4 60 https://github.com/Nesvilab/MSFragger
Philosopher v4.0.1 61 https://github.com/Nesvilab/philosopher
TMT-Integrator v1.0.0 62 https://github.com/huiyinc/TMT-Integrator
genomicWidgets 10 https://github.com/bzhanglab/genomicWidgets
maftools R package v2.10.0 63 https://bioconductor.org/packages/release/bioc/html/maftools.html
Immunedeconv v2.0.4 64 https://github.com/omnideconv/immunedeconv
CIBERSORT 65 https://cibersortx.stanford.edu/
xCell 66 https://github.com/dviraran/xCell
ESTIMATE 67 https://bioinformatics.mdanderson.org/public-software/estimate/
PROGENy v1.10.0 68 https://www.bioconductor.org/packages/release/bioc/html/progeny.html
SigProfilerMatrixGeneratorR v1.0 69 https://github.com/AlexandrovLab/SigProfilerMatrixGeneratorR
DoAbsolute v2.2 70 https://github.com/ShixiangWang/DoAbsolute
ABSOLUTE v1.0.6 71 http://www.broadinstitute.org/cancer/cga/ABSOLUTE
CNVEX 16 https://github.com/mctp/cnvex
Custom R scripts This paper https://doi.org/10.6084/m9.figshare.c.6690756