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. Author manuscript; available in PMC: 2024 Jul 31.
Published in final edited form as: Vaccine. 2023 Jul 6;41(34):4996–5002. doi: 10.1016/j.vaccine.2023.06.081

Figure 2. Examples of erythema induced at the bite site during tick challenge of selected mRNA LNP immunized animals.

Figure 2.

Guinea pigs were monitored following the tick challenge with 30 I. scapularis nymphs and erythema at the bite site was photographed until all ticks detached. The representative images show the backs of the animals immunized with Salp14 mRNA-LNP (severe erythema), IsPDIA3 mRNA-LNP (modest erythema) or control Luc mRNA-LNP (minimal erythema) at the indicated time points.