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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Biomaterials. 2023 Jul 13;301:122245. doi: 10.1016/j.biomaterials.2023.122245

Figure 3. Pino/ahNP reduces CD68 and active (cleaved) caspase-3 in injured Zucker rat carotid arteries.

Figure 3.

Obese Zucker rat carotid arteries were injured to induce IH, and drug-loaded ahNP or empty ahNP were pen-brushed on the adventitia. Pino: 0.3 mg/kg; Rapa: 0.018 mg/kg. Arteries were collected 28 days later. Green autofluorescence illuminates elastin laminae. Neointima is demarcated between arrows. Scale bar: 100 μm. Quantification: Data are presented as mean ± SEM of percent positively stained cells versus total cells; n = 4 rats. ANOVA and Tukey test: **P<0.01.