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. 2022 Jun 15;6:e2200147. doi: 10.1200/PO.22.00147

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© 2022 by American Society of Clinical Oncology

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FIG A1. — Differentially expressed genes in all unique BOSTON comparisons. Volcano plots showing all differential expression genes identified across response comparisons in the BOSTON XVd cohort. (A) PFS120, (B) PFS200, (C) PFS300, (D) PFS90, (E) PR, (F) PR_PFS120, (G) VGPR, (H) VGPR_PFS120, and (I) VGPRR_PFS300. Gene symbols are labeled where Adj P < .05 is in red for overexpression and blue for underexpression in responders to XVd therapy. Adj, adjusted; FC, fold change; PFS, progression-free survival; PR, partial response; VGPR, very good partial response; XVd, selinexor, bortezomib, and dexamethasone.