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. 2023 Sep 8;24(18):13853. doi: 10.3390/ijms241813853

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Histopathological analysis of the spinal cord around the lesion site. (A) HE-staining of coronal sections at the rostral (−5 mm), epicenter, and caudal (+5 mm) segments after SCI. The image shown includes the data closest to the mean. Scale bar, 500 μm. (B) Quantitative analysis of the HE-stained area in the axial sections (n = 8 animals in the control cell-transplanted group and n = 9 animals in the CiN cell-transplanted group). (C) A scatter plot shows the relationship between the spinal cord area (HE-stained area) and FA value at the rostral (−5 mm; left panel), epicenter (center panel), and caudal (+5 mm; right panel) sites. (D) LFB-staining of coronal sections at caudal (+5 mm) segments after SCI. The image shown includes the data closest to the mean. Scale bar, 500 μm. (E) Quantitative analysis of the LFB-stained area in the axial sections (n = 8 animals in the control cell-transplanted group and n = 9 animals in the CiN cell-transplanted group). (F) A scatter plot shows the relationship between the LFB-stained area and FA value at the caudal (+5 mm) site.