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SROC of GFAP in differentiating HS from IS at 3 h (A), 4.5 h (B) and 6 h (C). The summary AUCs were 0.945 (95% CI, 0.641–0.999), 0.915 (0.835–0.996), 0.849 (0.473–0.985) at 3 h, 4.5 h, 6 h, respectively. Each circle represents a study, with larger circles indicating larger sample sizes and higher weights. SROC, summary receiver operating characteristic; AUC, area under curve; GFAP, glial fibrillary acidic protein; IS, ischaemic stroke; HS, haemorrhagic stroke.
