Table 1.

Patent-related nanocarriers for treatment of Chagas disease.

Title of the Patent	Drug/Compound	Nanocarrier	Publication Number	Inventor	Country
Pharmaceutical compositions containing sesquiterpene lactones belonging to the class of furan heliangolides for the treatment of parasitic infections and tumors	Sesquiterpene lactones belonging to the class of furan heliangolides (Lycnofolide)	Polymeric nanoparticles	WO 2013/059898 A1 PI 1106302-5 A2	Mosqueira et al., 2013 and 2012 [19,20]	PCT and BRA
Nanoplatform production process for encapsulation and carrying of drugs and nanoplatform prepared from this	Benznidazole	(BNNS)-Chitosan nanoparticles	BR 102020019797-5 A2	De-Sousa et al., 2020 [21]	BRA
Pharmaceutical compositions of posaconazole and benznidazole with increase in dissolution	Pasoconazol and Benznidazole	Solid dispersion	BR 102016023800-5 A2	Rolim-Neto et al., 2016 [22]	BRA
Pharmaceutical formulations containing benznidazole and mof’s association for technological obtainment of drug delivery systems	Benznidazole	Metal–organic structures	BR 102016003408-6 A2	Rolim-Neto et al., 2016 [23]	BRA
Compositions and process of production of liquid form administration based on emulsion lipid systems, of emulsion, microemulsion and/or nanoemulsion type, containing benznidazole for the treatment of the Chagas disease	Benznidazole	Micro/ nanoemulsions	BR 102012019428-7 A2	De-Oliveira et al., 2012 [24]	BRA
Composition and production method of nanoparticulate systems for modified release of Benznidazole	Benznidazole	Polymeric or lipid nanoparticles	BR 102017024448-2 A2	Da-Silva-Junior et al., 2017 [25]	BRA
Compositions pharmaceutical and veterinary in Micro- and nanostructured forms and forming micro- and nanostructures in the gastrointestinal tract containing benznidazole and its derivatives and their biological applications	Benznidazole	Self-emulsifying	BR 102013023902-0 A2 WO 2015/039199 A1	Mosqueira et al., 2013 and 2015 [26,27]	BRA and PCT