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. 2023 Sep 8;24(18):13865. doi: 10.3390/ijms241813865

Figure 1.

Figure 1

S1PR1 and KLF2 are increased during HIV infection in the thymus at 5 and 9 weeks. (A) Schematic of HIS mouse model including infection with NL4-3 (n = 5) or mock-infected (n = 4) and ex-vivo assays performed at 5 weeks post-infection. (B) and (C) S1PR1 and KLF-2 mRNA expression increase at 5 weeks post-infection. The expression of each gene relative to the housekeeping gene (GAPDH) expression is shown. (D) Schematic of the HIS mouse model including infection with NL4-3 (n = 7) or mock-infected (n = 4) and ex-vivo assays performed at 9 weeks post-infection. (E) and (F) S1PR1 and KLF2 mRNA expression increase at 9 weeks post-infection. The expression of each gene relative to the housekeeping gene (GAPDH) expression is shown. In Figure (B,C) and (E,F), the mean with the standard error of the mean (SEM) is shown and two-tailed unpaired t-tests were used for all comparisons.