Skip to main content
. 2023 Sep 8;24(18):13865. doi: 10.3390/ijms241813865

Figure 4.

Figure 4

Akt signaling is not impaired during HIV infection in the thymus. Akt phosphorylation was examined by phospho-flow staining following two weeks of infection with dual-tropic HIV in BLT mice (n = 5 mock and n = 6 HIV-1; n = 11 total). (A) There is no significant difference in the percentage of pAkt-expressing total thymocytes between mock and HIV-infected animals (p = 0.47 by unpaired two-tailed t-test) upon exposure of thymocytes to S1P for 30 min. (B) There is no significant difference (p = 0.5) in the percentage of pAkt-expressing mature CD3hiCD69− thymocytes between mock and HIV-infected animals by two-tailed unpaired t-test.