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. 2023 Aug 28;14(9):1711. doi: 10.3390/genes14091711

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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AlphaFold structural predictions for proteins with polyP containing IDRs. The polyP is represented in blue, including the side chain represented with sticks. (a) Predicted structure for protein Q8IWV7-UBR1_HUMAN-E3 ubiquitin-protein ligase UBR1, which presents the highest pLDDT we observed for a polyP in an IDR and for the corresponding IDR. (b) Predicted structure for protein Q9NP73-ALG13_HUMAN-Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13. This protein presents the longest polyP in our dataset, with 27 residues.