Table 1.

(a): Demographics, cognitive profiles and cerebrospinal fluid biomarker profiles of the discovery cohort. Abbreviations: AD, Alzheimer’s disease; MMSE, mini mental score exam; CSF, cerebrospinal fluid. All data are shown as the mean ± standard deviation unless otherwise stated. (b): Demographics and cognitive profiles of the validation cohort. Abbreviations: AD, Alzheimer’s disease. All data are shown as the mean ± standard deviation unless otherwise stated.

(a)
	AD (n = 6)	Control (n = 5)
Sex (% Male)	50	75
Age (years)	59.2 ± 4.1	59.3 ± 3.9
Positive APO ε4 status (%)	83	Not tested
MMSE score	24.2 ± 3.5	29.4 ± 0.9
CSF Aβ1-42 (pg/mL)	453 ± 93.4	1073.2 ± 196.5
CSF T-tau (pg/mL)	1407 ± 985.3	304 ± 80.1
CSF P-tau 181 (pg/mL)	121.4 ±89.5	42.4 ± 8.0
BMI	24.1 ± 2.3	25.98 ± 2.2
(b)
	AD (N = 9)	Control (N = 12)
Sex (% Male)	67	50
Age (years)	62.3 ± 3.0	59.1 ± 6.6