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. 2023 Sep 15;24(18):14154. doi: 10.3390/ijms241814154

Figure 2.

Figure 2

The 3D structure of the putative ALOX15 of N. furzeri exhibits a high degree of strutural similarity with (A) human ALOX15B, (B) rabbit ALOX15, and (C) human ALOX12. Three-dimensional structural models were worked out for the putative bony fish ALOX15 orthologs on the basis of the X-ray coordinates of human ALOX15B [32] as described in the Materials and Methods section. The model of the N. furzeri enzyme (turquoise) was overlaid with the 3D strutures of rabbit ALOX15 (mangenta, PDB: 2P0M), human ALOX15B (blue, PDB: 4NRE), and human ALOX12 (brown, home-made model).