Table 2.
Independent Variable | Univariate Analysis | |
---|---|---|
HR (95% CI) | p-Value | |
Male gender | 2.71 (1.04–7.06) | 0.041 |
Age | 1.11 (1.05–1.17) | <0.0001 |
Splenectomy | 1.75 (0.67–4.54) | 0.254 |
Pretransfusion hemoglobin | 1.12 (0.49–2.56) | 0.780 |
Serum ferritin | 1.00 (0.99–1.00) | 0.549 |
Diabetes | 3.15 (1.21–8.19) | 0.019 |
MRI LIC | 1.02 (0.99–1.05) | 0.113 |
Global pancreas T2* | 0.89 (0.81–0.98) | 0.015 |
Global heart T2* | 0.99 (0.95–1.04) | 0.893 |
N. of segments with T2* < 20 ms | 0.99 (0.88–1.11) | 0.831 |
LV EDVI | 1.00 (0.97–1.03) | 0.915 |
LV EF | 1.03 (0.96–1.11) | 0.409 |
LV mass index | 1.01 (0.98–1.05) | 0.580 |
RV EDVI | 0.99 (0.97–1.03) | 0.870 |
RV EF | 1.06 (0.99–1.13) | 0.122 |
Replacement myocardial fibrosis | 1.46 (0.27–7.99) | 0.662 |
Left atrial area index | 1.31 (1.16–1.49) | <0.0001 |
Right atrial area index | 1.29 (1.12–1.45) | <0.0001 |
HR = hazard ratio, CI = confidence interval, MRI = magnetic resonance imaging, LIC = liver iron concentration, LV = left ventricular, EDVI = end-diastolic volume index, EF = ejection fraction, and RV = right ventricular.