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. 2023 Sep 18;24(18):14234. doi: 10.3390/ijms241814234

Scheme 11.

Scheme 11

Proposed mechanism of acid-catalyzed heterocyclization of 1,2,4-triketone analogs 1 and 2ac into regioisomeric 3- and 5-acetylpyrazoles and pyridazinones.